Columbia University
Irving Medical Center
Neurological Institute
710 West 168th Street, 3rd floor
(212) 305-1818
TaubCONNECT Research Perspectives:
2017 Archive
Neuronal Hyperactivity Due to Loss of Inhibitory Tone in APOE4 Mice Lacking Alzheimer's Disease-Like Pathology
and
The Endosomal–Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo
First Place: A CSF Proteomic Screen Links Retromer to Alzheimer's Pathogenic Pathways and Suggests Endosomal-Trafficking Biomarkers
First Place: Microglia Identity in the Aged and AD Human Brain
Intra-Axonal Synthesis of SNAP25 is Required for the Formation of Presynaptic Terminals
Stabilization of Dynamic Microtubules by mDia1 Drives Tau-dependent Aβ1-42 Synaptotoxicity
An xQTL Map Integrates the Genetic Architecture of the Human Brain's Transcriptome and Epigenome
LTP and Memory Impairment Caused by Extracellular Aβ and Tau Oligomers is APP-Dependent
Neuropathologic Features of TOMM40 '523 Variant on Late-Life Cognitive Decline
An Approach to Studying the Neural Correlates of Reserve
Brain Atrophy Can Introduce Age-Related Differences in BOLD Response
Age-Related Biomarkers in LLFS Families With Exceptional Cognitive Abilities
Polygenic Risk Scores in Familial Alzheimer Diseases
Local Synthesis of Dynein Cofactors Matches Retrograde Transport to Acutely Changing Demands
Novel Genetic Loci Underlying Human Intracranial Volume Identified Through Genome-Wide Association
Relation of Dysglycemia to Structural Brain Changes in a Multiethnic Elderly Cohort
Unbiased Drug Screening Identified New Cellular Pathways that Regulate Apolipoprotein E Secretion in Human Primary Astrocytes
Activating Transcription Factor 4 (ATF4) Modulates Rho GTPase Levels and Function via Regulation of RhoGDIα
First Place: White Matter Changes in Alzheimer's Disease
Alzheimer's Association International Conference (AAIC 2016)
Neuronal Activity Enhances Tau Propagation and Tau Pathology in Vivo
Sleep Disordered Breathing and White Matter Hyperintensities in Community-Dwelling Elders
Dementia Risk and Protective Factors Differ in the Context of Memory Trajectory Groups
Parkinson's Disease: Guilt by Genetic Association
PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease
Tau-driven 26S Proteasome Impairment and Cognitive Dysfunction can be Prevented Early in Disease by Activating cAMP-PKA Signaling
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
Examining the Pathways Between Self-Awareness and Well-Being in Mild to Moderate Alzheimer Disease
Mediterranean Diet and Brain Structure in a Multiethnic Elderly Cohort
Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates
Telomere Longitudinal Shortening as a Biomarker for Dementia Status of Adults With Down Syndrome
Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease
First Place: DREADDs Activation in the Medial Entorhinal Cortex (MEC) of EC-Tau Mice
F-box/LRR-repeat Protein 7 is Genetically Associated with Alzheimer's Disease
The Keystone of Alzheimer Pathogenesis Might be Sought in Aβ Physiology
Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
SUMO1 Affects Synaptic Function, Spine Density and Memory
Connectivity and Circuitry in a Dish Versus in a Brain
Self-Efficacy Buffers the Relationship between Educational Disadvantage and Executive Functioning
Specific Downregulation of Hippocampal ATF4 Reveals a Necessary Role in Synaptic Plasticity and Memory
Mediterranean Diet and Leukocyte Telomere Length in a Multi-ethnic Elderly Population
Neurotherapeutics: Rethinking Alzheimer's Disease Therapies
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau
Olfactory deficits predict cognitive decline and Alzheimer dementia in an urban community
Regulation of Synaptic Plasticity and Cognition by SUMO in Normal Physiology and Alzheimer's Disease
Lobar Microbleeds are Associated with a Decline in Executive Functioning in Older Adults
Targeting Axonal Protein Synthesis in Neuroregeneration and Degeneration
Coding Mutations in SORL1 and Alzheimer's Disease
First Place: Pathogenic Role of Formin-mediated Stable Detyrosinated Microtubule Inductionby Amyloid Beta
Soluble Amyloid Beta Levels are Elevated in the White Matter of Alzheimer's Patients, Independent of Cortical Plaque Severity
Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal Across Brain Regions
Neurological Disorders: Quality-control Pathway Unlocked
Estrogen Receptor β Variants Modify Risk for Alzheimer's Disease in a Multiethnic Female Cohort
Local Synthesis of TC10 is Required for Membrane Expansion During Axon Outgrowth
Dynamin 1 is Required for Memory Formation
Behavioral Assays with Mouse Models of Alzheimer's Disease: Practical Considerations and Guidelines
Biobanked Alzheimer's Brain Tissue Yields Living Neurons
Picomolar Amyloid-ß Peptides Enhance Spontaneous Astrocyte Calcium Transients