Taub Institute: Genomics Core


Columbia University
Irving Medical Center
Neurological Institute

710 West 168th Street, 3rd floor
(212) 305-1818

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About Us

Taub Faculty

 Andrew Sproul, PhD

Andrew Sproul, PhD

Assistant Professor of Pathology and Cell Biology (in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) at the CUMC
Director of the Stem Cells and Cellular Models Platform, Taub Institute

Email: aas2003@cumc.columbia.edu
Tel: 646-379-1812

Research Summary:

I am the founding Director of the Stem Cell and Cellular Models Platform at the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, a core facility that was established with the goal to implement pluripotent stem cell technology as a resource for neurodegenerative and neurological disease researchers at Columbia University. Our laboratory's main focus is developing robust differentiation protocols for large-scale production of disease-relevant neurons and other CNS cell types, and using gene-editing strategies to create allelic series of isogenic disease and control pluripotent stem cell (PSC) lines. These tools will greatly aid mechanistic studies of disease mechanisms and provide a better platform for therapeutic screening. In addition to partnering with a variety of Taub investigators on disease-related research, our laboratory is interested in elucidating novel mechanistic links between aberrant APP processing and Tau dysregulation.

Education and Training:

PhD: Columbia University, 2008

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