Dr. Mayeux has been the author of over 300 papers, chapters and books dealing with various aspects of Alzheimer disease and other degenerative diseases of the aging brain.

He received the Leadership and Excellence in Alzheimer disease Award from the National Institute of Aging for his investigation of genetic and environmental interaction in the etiology and pathogenesis of Alzheimer disease and related forms of dementia. He is an elected member of the Association of American Physicians, the American Epidemiological Society and The Institute of Medicine of the National Academies.

Dr. Mayeux has led a multidisciplinary, population-based, epidemiological investigation of Alzheimer disease and related conditions known as the Washington Heights-Inwood Community Aging Project. This study has provided the most current information on the rates of these diseases among elderly from African-American, Caribbean Hispanic and Whites in these urban communities. This study has provided information on the relationship between Alzheimer disease and hormone replacement therapy in postmenopausal women; genotypic variability of APOE risk in different ethnic groups; and the relationship of alterations in lipid metabolism and risk of dementia. His current research involves genetic investigation of Alzheimer’s disease in Caribbean Hispanic families with and studies of the heritability of longevity.