Dr. Cosentino's research has examined the cognitive, behavioral, and metacognitive profiles of various neurodegenerative diseases, particularly Alzheimer's disease and Frontotemporal dementia (FTD). The overarching goals of her current work are to characterize the factors that explain metacognitive variability along the spectrum of healthy to pathological aging, and to identify the practical consequences of metacognitive impairment for everyday decision making and quality of life.

A related goal is the examination, refinement and development of tools to assess subjective cognition and metacognition in older adults in order to clarify the prognostic relevance of cognitive complaints in healthy older adults and the nature of disordered metacognition in neurodegenerative conditions.